A great study published in Frontiers of Veterinary Science titled ‘Pharmacokinetics, Safety, ad Clincal Efficacy of Cannabidiol Treatment in Osteoarthrititc Dogs’ by Gamble et. al (2018) discusses how CBD helps.
One point from the study that is very interesting discusses that the half-life of CBD in doggies appears to be 4-5 hours with terminal half-life at 9 hours. In humans, it has been demonstrated that half-life extends as far as 18-33 hours.
For this study, the researchers used CBD in olive oil. Olive oil is a good oil to use for a tincture base but we prefer to use hemp oil due to its superior omega 3:6 ratio. Although olive oil contributes omega:9, we prefer to use the grape seed oil. Regardless, use of a tincture for humans or animals is preferred as it allows for consistent dosing. In addition, CBD is lipophilic (it likes to be in oil form) and dosing was found in the study to be best at 2x/day.
The authors also discussed all the available research on the topic of CBD and its effects with dog health. The topics include:
1. Reduction of pain and inflammation
2. Reduction of anxiety and phobia
3. Aiding with digestive system issues
4. Reduction of Pruritis (itching)
5. Protection from immune-mediated and inflammatory allergic disorder
6. Anticonvulsant and anti-epileptic effects
In this study, it was found that 2mg/kg of CBD twice daily helped with increasing comfort and activity with dogs suffering from osteoarthritis. At Noetic Nutraceuticals,, we are more interested in the absolute effect of CBD more-so than the dosing what was used in the study.
Wait a second, how can we say this? Doesn’t the study prove that a certain dose works? Well, yes and no. A certain dose is shown to work but who’s to say using less will not work? This is the inherent issue with CBD and those who produce it for commercial products. Because we are dealing with the neurological system, there is no 100% standard. This is why we offer treats and a daily tincture for your fuzzy friend.